8/31/2023 0 Comments Cell signal![]() 1 Structurally, diverse concepts have been considered to construct the cell-like compartments, such as giant unilamellar vesicles (GUVs), 2 hydrogels, 3 polymersomes, 4 coacervates, 5 etc. 19, 487–496 (2018).Artificial cells (ACs) are nano/micron-sized compartments assembled with natural and/or synthetic materials, typically focusing on mimicking one or more structural/functional features of living cells. use a toolbox of chemical and biology techniques and advanced quantitative imaging to elucidate further key details about the role of the heterogeneity of the lipid environment in the initiation of B cell signaling 2. In this issue of Nature Chemical Biology, Shelby et al. However, the exact mechanism that tips the balance from a resting cell to an activated cell remains under debate. ![]() This protein sorting could be driven by protein size, charge or conformational change, variations in protein mobility or immobilization, or changes in membrane lipid organization (reviewed in ref. After the antigen has docked to the receptor on the surface of the immune cell, the initiation of immune cell signaling requires extensive spatial reorganization of multiple proteins at the plasma membrane, such as receptors and co-receptors, activating and inhibiting enzymes, etc. Scientists have long marveled about the way that an immune cell can robustly and specifically respond to a single target molecule of one kind.
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